In the movie, the signal consists of a series of pulses that match the sequence of prime numbers (2, 3, 5, 7, 11…), which is highly unlikely to occur by chance in nature since most natural signals, such as those from stars or pulsars, follow simple, predictable patterns (like regular pulses, sine waves, or random noise) caused by physical phenomena, while prime numbers, are in an irregualr sequence where the patterns of distribution remain a mystery. The use of prime numbers immediately alerts the protagonist, Ellie, that the signal is not a random phenomenon but potentially a deliberate attempt at communication by an intelligent source.